Methodology and Statistics
Tilburg School of Social and Behavioral Sciences
Phone: +31 (0) 13 466 3687 (secretary)
Academic webpage Xynthia Kavelaars
Making the most of clinical trials: Increasing efficiency using novel Bayesian methods for information-sharing within and between trials
Randomized controlled trials (RCTs) are considered the gold standard to investigate effectiveness of new treatments. However, as treatments become more personalized and address smaller subpopulations it becomes increasingly hard to setup powerful trials. We solve this problem by developing novel methods that 1) combine data from different endpoints within a trial, 2) include evidence from similar trials using different endpoints, and 3) include evidence from similar trials conducted on different groups of patients.
We will develop and evaluate a Bayesian framework for information sharing within and between trials to advance the efficiency of RCTs.
Prof.dr. M.C. Kaptein, dr.ir. J. Mulder
NWO Research Talent Program
1 July 2018 – 31 June 2022